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For these patients, oral B12 supplementation (1,000-2,000 mcg daily sublingual methylcobalamin) provides comparable B12 repletion without injection

Minutes after initial stimulation, neutrophils switch from primarily using glycolysis for basal metabolism, to the PPP, in order to allow for rapid generation of NADPH ( Brisk production of NADPH through the PPP is itself linked to sufficient basal and reserve capacity of G6PD enzyme activity ( Figure 1A )

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