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Dysregulation of KEAP1-NRF2 activity has been extensively demonstrated in cellular and animal models of ALS and in postmortem ALS motor cortex and spinal cord samples, so dysregulation of the NRF2/ARE antioxidant and cytoprotective pathway could be a possible mechanism underlying the progressive neurodegeneration in ALS and severity of the disease
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10.1055/s-0043-109563 29
Because GLP-1 medications slow stomach emptying, tell your provider and anesthesia team about any upcoming surgery, procedure, anesthesia, or deep sedation
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