Acknowledgements This study was supported by grants from the Chang Gung Memorial Foundation (CMRPG-5D0111, CMRPG2F0171, CMRPG2F0172, CMRPG2F0173, CMRPG-2G0361, CMRPG-2H0161, CRRPG2H0162, CMRPG-2J0261, CMRPG-2K0091, CORPG2N0141, CORPG2P0231, and CORPG2P0191), the Ministry of Science and Technology, Taiwan (104-2320-B-182A-013, 106-2314-B-182A-064, 107-2314-B-182A-138, 108-2320-B-182A-009-MY3, 108-2314-B-182A-027, 108-2321-B-182-003 and 109-2321-B-182-001) and the Taiwanese Ministry of Health and Welfare (MOHW110-TDU-B-212-124005, MOHW111-TDU-B-212-134005, MOHW112-TDU-B-212-144005)
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Note the larger hair follicles (elongated columns) in the lower photo, the increased content of subcutaneous fat in the skin (white material in the center of the skin), and the increased thickness of the skin
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