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Do not freeze the constituted nasal spray solution
Other shared risks include possible pancreatitis, gallbladder disease and theoretical concerns about medullary thyroid carcinoma, based on preclinical models 9
Extreme calorie deficits create another problem
The FDA approved tirzepatide only as a subcutaneous injection, first as Mounjaro for type 2 diabetes in May 2022, then as Zepbound for chronic weight management in November 2023
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