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Journal of Medicinal Chemistry (2021) 7

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As mentioned, a secondary analysis of an RCT assessing the cardiometabolic effects of exenatide in 40 people with schizophrenia 140 also looked at measures of cognition and psychosocial functioning (that is, Brief Assessment of Cognition in Schizophrenia, ReyOsterreith Complex Figure Test, Short-Form Health Survey, Personal and Social Performance Scale, Positive and Negative Syndrome Scale), but found no effect for this GLP-1RA compared with placebo over 3 months 133

The core itself consists of a D1 (PsbA) and D2 (PsbD) heterodimer, binding redox-active cofactors near the reaction center for electron transfer