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An intermittent cold stress (ICS) fibromyalgia mouse model showed that 4-amino-3-(phenylselenyl)benzenesulfonamide (4-APSB), a selenium-sulfa compound with antioxidant properties reduces oxidative stress and neuroinflammation by activating NRF2, leading to enhanced antioxidant defense, lower IL-1/TNF-, and reduced pain and depressive-like behaviors (13)
This ratio reflects the redox state of the cell and is crucial in studies of cellular response to oxidative stress and toxicity
The improvement is not only about fewer lines but also better texture and more even tone
W., Lorenzini, I., Liu, F., et al
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