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Mach, Genve (Cardiologie)
Combining both compounds targets insulin resistance from two independent angles
Based on general principles applicable to subcutaneous injectable therapies: Those who do not rotate injection sites adequately , leading to repeated trauma to the same area Individuals on concomitant anticoagulant therapy (for example, warfarin or direct oral anticoagulants), who may experience more pronounced bruising People with a history of allergic skin conditions , who may be more prone to localised irritation, though this has not been specifically studied for retatrutide It should be noted that risk factors relating to specific excipients or the effect of body mass index on injection site reactions cannot be confirmed at this stage, as retatrutide's final formulation details are not yet publicly available in a licensed SmPC
The two most studied incretin hormones are GLP-1 and GIP, produced in response to nutrients entering the gastrointestinal tract, mediated by G-protein-coupled receptors on -cells [18]
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