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Older adults and people with more serious, chronic challenges are less fortunate, and some people have adverse effects with high levels of NAC use

Recent surgeries, heart attacks, or strokes can also increase vulnerability to this serious side effect

Inflammatory mediators Tissue injury, however minor, initiates a localised inflammatory cascade involving histamine, prostaglandins, and cytokines, which sensitise nerve endings and cause the characteristic burning or stinging sensation

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