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Red flags in documentation include: Generic COAs that do not reference a specific batch or lot number COAs with identical data across different batches (suggesting the document is fabricated) Refusal to provide COA before purchase Testing laboratory names that cannot be verified as real entities HPLC chromatograms that appear altered or inconsistent with stated purity values Missing mass spectrometry data If you cannot verify the authenticity of a supplier COA, send a sample to an independent lab before ordering in bulk

Most of what we know comes from animal research, where issues like lower birth weight, pregnancy loss, and developmental delays were seen

Moreover, treatment strategies for AP have undergone significant evolution, shifting from traditional open surgical approaches toward more refined, stage specific, and personalized intervention models

doi: 10.1007/s12672-025-02471-w