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Such mutations, if they occur in critical genes like oncogenes or tumor suppressor genes, can drive the transformation of normal cells into malignant ones [98]
Immunologic mechanisms includes a greater Th2/Th1 ratio to increase the production of IgE, leading to greater allergic sensitization [30]
Abstract Gut microbial dysbiosis is associated with the development of autoimmune disease, but the mechanisms by which microbial dysbiosis affects the transition from asymptomatic autoimmunity to inflammatory disease are incompletely characterized
I., Lin'kova, N
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