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Seek medical attention immediately if fatigue is accompanied by symptoms suggestive of hypoglycemia, particularly if you are taking insulin or sulfonylureas in addition to semaglutide

While GLP-1 shots are generally well-tolerated, some patients may experience side effects that make it difficult or undesirable to continue treatment

In some cases, doctors may also recommend testing the following as well: Pancreatic enzymes (amylase and lipase) if a patient develops symptoms suggestive of pancreatitis, which is a rare but serious potential side effect

If you are working with an online personal trainer during your retatrutide protocol, that window becomes much more useful