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Tirzepatide , the dual GIP/GLP-1 receptor agonist, has demonstrated mean heart rate increases of approximately 2-4 beats per minute in the SURPASS clinical trial program, as reflected in the Mounjaro and Zepbound prescribing information
Compared with groups A1, 2 and 3, the Johnsen scores were decreased in groups B, C and D, and the difference was statistically significant ( P 0.05)
Individual outcomes differ
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