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It has emerged as a life-changing option for overweight or obese people who are committed to shedding a significant amount of weight and do not have other significant underlying health issues

Phase I detoxification involves the cytochrome P450 enzyme system, which breaks down fat-soluble toxinssuch as pharmaceutical medications, heavy metals, mold mycotoxins, and metabolic wasteinto intermediate compounds

Once inside the cell, Fe 3+ is reduced to Fe 2+ via six-transmembrane epithelial antigen of prostate 3 (STEAP3) and transported into the cytosol by divalent metal transporter 1 (DMT1) and ZRT/IRT-like proteins 8 and 14 (ZIP8/14) (Wang et al., 2025d)

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