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S., Gelfanov, V., Lindsey, S

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J Neurosci 15(11):73447356

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As reported by Ibrahim et al., SCO promoted the polarization of microglia toward an M2 subtype by shutting down the TLR4/MyD88/TRAF-6/TAK-1/NF-B axis and inhibiting the NLRP3 pathway, and effectively mitigated ovariectomy/D-galactose(OVX/D-Gal)-induced neuroinflammation and neuronal degeneration, leading to a reduction in neuroinflammation and neurodegeneration in OVX/D-Gal models of Alzheimers disease (63)

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IV glutathione has been studied in selected medical contexts

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