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It has been widely studied in preclinical models for its potential to support tissue regeneration , angiogenesis , and inflammation modulation
Reported issues include dosing errors and quality/handling problems (FDA safety communication, updated 2025)
During the trial, additional anti-diabetic medication was initiated as an add on to randomized treatment by 4.9%, 1.1 % and 2.2% of patients randomized to placebo, semaglutide tablets 7 mg and semaglutide tablets 14 mg, respectively
This study does, however, have limitations typical of real-world data and we recognise the early exploratory nature of our work would benefit from further dedicated longitudinal studies with more robust design methodology in order to confirm our findings
