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Apc-derived cytokines and T cell polarization in autoimmune inflammation

There is a kernel of truth to this the FDA has noted that peptides can have fewer off-target effects than many small-molecule drugs

How the side effects compare Because both drugs act on the same hormone pathway, their side-effect profiles look broadly alike, and the problems are mostly digestive and tend to track the dose

The authors show that LXA4 activates the expression of GPX4, lysophosphatidic acid receptor-3 (LPAR3), and estrogen receptor beta (ESR2) in FLSs, which inhibits ferroptosis and reduces inflammation and chondrocyte matrix breakdown