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Symptoms often develop gradually and include: Feeling tired and weak Feeling colder than normal Weight gain despite not eating more Dry skin and thinning hair Low mood and foggy thinking Constipation Muscle aches and joint pain Research shows that people with hypothyroidism typically burn 100-400 fewer calories per day compared to those with normal thyroid function

Key takeaways Contrave (bupropion and naltrexone) is an oral medication

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Ethics declarations Competing interests All the authors declared that no competing interests