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Metformin, if not contraindicated, is the preferred first line pharmacological agent for type 2 diabetes 14
The results were equally promising: Social communication improved significantly (CARS scores decreased from 38.3 to 33.2)
The second is the patent that Novo either overlooked or decided not to maintain
The question of whether GLP-1 therapy qualifies as direct immunomodulation or whether the benefits are primarily mediated through weight loss and reduced adipose inflammation is still under active investigation
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