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Headaches Often due to: Dehydration Reduced food intake Electrolyte imbalance Less Common but Important Side Effects Acid reflux Dizziness Injection site irritation These are usually mild but should not be ignored if persistent

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This is substantiated by two large, randomized placebo-controlled trials, the Womens Health Initiative study 11 and the Heart and Estrogen/Progestin Replacement study 12 that found a significant reduction in the incidence of diabetes in women assigned to menopausal estrogen therapy, thus providing evidence for the antidiabetic action of estrogen in women

They didnt irritate my skin and worked well to soothe redness around my cheeks