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Glutathione is present in millimolar concentrations in most mammalian cells and it is involved in several fundamental biological functions, including free radical scavenging, detoxification of xenobiotics and carcinogens, redox reactions, biosynthesis of DNA, proteins and leukotrienes, as well as neurotransmission/neuromodulation

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The EGC constitutes a fundamental model to investigate the composition and the activation of the microbicide system of the phagocyte cells, especially of the neutrophil ones