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By mimicking the hormone glucagon-like peptide-1, semaglutide slows gastric emptying, promotes insulin secretion, and reduces appetitemechanisms confirmed across GLP-1 research and the SUSTAIN clinical trial program (Sorli 2017)

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Granata A, Maccarrone R, Anzaldi M, Leonardi G, Pesce F, Amico F, et al (2022) GLP-1 receptor agonists and renal outcomes in patients with diabetes mellitus type 2 and diabetic kidney disease: State of the art