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Although the high dose (15 mg/kg) was used to indicate the effect of cyclosporine treated rats, rather than the actual dose used for humans (2.5 mg/kg), results demonstrate that cyclosporine medication can harm liver function and cause oxidative stress and redox imbalances in rat hepatocytes ( The mechanism by which cyclosporine induces oxygen species As a potent immunosuppressant, the major therapeutic effect of cyclosporine is the suppression of T-cell activity

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Such measures remove the need for long-term administration of cyanocobalamin

PMID: 16056068