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Additionally, glutathione disulfide (GSSG) is involved in the degradation of drug delivery systems containing disulfide bonds, which allows for targeted drug release in cancer therapy

Keywords : pancreatic cancer, TXNDC12, GGT7, GSH, ferroptosis, progression As a highly malignant tumour in the digestive system, PAAD has become one of the major public health problems worldwide due to its rapid progression and poor clinical prognosis [1]

Cytoplasmic HMGB1 induces renal tubular ferroptosis after ischemia/reperfusion

This separation suggests theoretical safety for concurrent use, though formal drug-interaction studies have not been published in peer-reviewed journals