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250 Therefore, targeting dyslipidemia and its downstream effects may offer promising therapeutic avenues for DPN management (Fig

Williams, A novel role for vitamin B12: Cobalamins are intracellular antioxidants in vitro, Free Radical Biology and Medicine, Volume 47, Issue 2, 15 July 2009, Pages 184-188, ISSN 0891-5849, J

For now, however, the findings are preliminary and come primarily from laboratory experiments and a mouse model, not human clinical trials

These events lead to a state of persistent inflammation and chronic oxidative stress (8285), characterized by increased ROS production, reduced GSH peroxidase activity, selenium deficiency and reduced GSH levels (8091)