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328 It is important to note that treatment for such a complex disorder can take time to be effective
The NOAEL established in 90-day rat toxicology studies is 50mg/kg daily, which translates to a human-equivalent dose of approximately 560mg daily using FDA allometric scaling
People using a GLP-1 and no insulin were matched, 1:1, with those using insulin and no GLP-1 in the first analysis
Hence, both cilostamide and the GLP-1R stimulation most likely elevated cAMP in HAP
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