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Common strategies include: Prior authorization requirements to confirm medical necessity Body mass index (BMI) thresholds and comorbidity criteria Step therapy programs requiring lower-cost treatments first Participation in lifestyle or weight-management programs Higher formulary tiers with increased employee cost-sharing Some employers also limit prescribing authority to specific provider types or establish lifetime or annual spending caps where permitted under applicable regulations

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A trial participant in the phase III trial of its once-daily pill experienced "potential drug-induced liver injury" that disappeared after the participant stopped the pill, the company said in a statement