Summary: GLP-1 receptor agonists can modestly reduce systolic blood pressure by approximately 24 mmHg, though they are not licensed specifically as antihypertensive medications in the UK
In SURPASS-2, which compared tirzepatide to semaglutide (a GLP-1 receptor agonist) in patients taking metformin, tirzepatide 5 mg, 10 mg, and 15 mg doses achieved mean HbA1c reductions of 2.01%, 2.24%, and 2.30% respectively from baseline, compared to 1.86% with semaglutide 1 mg
Talk with your prescriber about: Pen versus vial Needle size Safe disposal What Trials Show About Weight Loss: How Much And How Fast Clinical trials show meaningful weight reductions with both drugs
Second, if you do not realize your medication is degraded and attribute your lack of results to other factors, you might make unnecessary changes to your diet, exercise, or dose