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Benefits of morning dosing: Enhances fat oxidation throughout the day Supports metabolic flexibility Provides energy and mental clarity Works synergistically with intermittent fasting protocols This timing is particularly effective when combined with other peptides

Vitamin B12 monitoring is particularly important for patients also taking metformin, as both medications can affect B12 status

Overall, mean age was 42.7 years, BMI was 42.0, mean waist circumference was 120.8 cm and 83% were female, with a substantial representation of Black patients (16% to 18%)