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Rictor/mTORC2 loss in the Myf5 lineage reprograms brown fat metabolism and protects mice against obesity and metabolic disease
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In the SURMOUNT-5 trial, tirzepatide resulted in a mean weight loss of 20.2% at 72 weeks, with 80% of participants achieving at least 10% weight loss and nearly 50% reaching 20% or more
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