The 50% buffer addresses all these possibilities while remaining within reasonable customs limits (most countries allow 30-90 days personal supply)
Signs of pancreatitis, severe nausea, or persistent GI symptoms warrant dosage review or discontinuation
Some GLP-1 in circulating blood binds directly to receptors in the pancreas to prompt the release of insulin
Fujishima Y, Maeda N, Inoue K, Kashine S, Nishizawa H, Hirata A, Kozawa J, Yasuda T, Okita K, Imagawa A, Funahashi T, Shimomura I: Efficacy of liraglutide, a glucagon-like peptide-1 (GLP-1) analogue, on body weight, eating behavior, and glycemic control, in Japanese obese type 2 diabetes