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Recently, different in vitro and in vivo studies reported sepsis-induced changes in the shape of human erythrocytes, which have also been confirmed in animal models and humans [126, 381,382,383,384,385,386,387,388,389]
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For example, in 2015, a randomized clinical trial of elderly men with sarcopenia found that 15g of daily collagen peptide supplementation, in combination with resistance training, led to improvements in multiple parameters: muscle strength, fat mass, and fat-free mass.40 For another example, a 2023 study of subjects with ultrasound-confirmed musculoskeletal inflammation concluded that locally injected collagen peptides could effectively and safely treat collateral ligament pain, indicating positive implications for physical recovery.41 It isnt clear how collagen compares to other peptides in facilitating these outcomes, as head-to-head studies arent available
