Thus, TNBS promotes two independent mechanisms of injury, GSH depletion and ROS generation, both being required for the manifestation of mucosal injury as GSH limitation renders intestine susceptible to the TNBS-induced ROS overgeneration
Esophageal squamous cell carcinoma (ESCC) is one of the major histological subtypes of esophageal cancer in China
Zhang, Y., Zhang, H., Ghosh, D., & Williams, R
Although considerable studies have demonstrated the protective effect of SCFAs on DN, there are still some controversies in this field, and their specific mechanisms in renal tubular cells, podocytes, and mesangial cells are not clear