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rare complications include allergic reactions and hypokalaemia during treatment of severe anaemia
Check your vial dates and storage history before assuming the medication is to blame
Particles can come from: Degraded peptide forming insoluble aggregates Contamination during manufacturing or storage Rubber stopper fragments from repeated needle punctures Crystallization of dissolved components If you see particles, do not try to filter them out
The gene responsible for the cobalamin C defect is the MMACHC, located on chromosome 1p34.1 (147)
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