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A TikTok trend where young women call themselves skinny fat meaning slim but not toned only compounds this

Cardiovascular Benefits: Weight reduction and a low-fat diet, with or without GLP-1 RAs, help lower blood pressure and reduce LDL cholesterol

Without 2+ years of consistent training history and a clear handle on what their body responds to without supplementation

Key limitations include: Lack of denominator data to calculate true event rates Potential reporting bias following regulatory or media attention Limited clinical information, including comorbidities, disease severity, and laterality Shorter market availability for tirzepatide vs semaglutide The authors called for longitudinal pharmacoepidemiologic studies with exposure denominators and prospective risk stratification to clarify whether a causal relationship exists