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A meta-analysis of RCTs and cohort studies showed that SGLT2 inhibitors reduce the risk of AKI across diverse cardiovascular risk profiles [59,109], and are associated with lower mortality, major adverse kidney events, and MACE in acute kidney disease [110]
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Genome-wide analysis of the general stress response network in Escherichia coli : sigmaS-dependent genes, promoters, and sigma factor selectivity
Pancreatic safety of incretin-based drugsFDA and EMA assessment
These documented medical conditions go far beyond the mild nausea and digestive discomfort commonly associated with these drugs, instead representing life-altering complications requiring hospitalization, surgical intervention, and ongoing medical management
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