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[28] [29] A critical limitation in interpreting available evidence is the difficulty distinguishing lipedema fat from concurrent obesity
The NF-B pathway functions as a central pro-survival and pro-inflammatory transcription factor that promotes tumor progression by suppressing tumor suppressors such as phosphatase and tensin homolog (PTEN), thereby indirectly enhancing PI3K/AKT signaling and supporting cancer cell viability
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Due to interpatient variability, fixed-dose regimens rarely achieve optimal efficacy
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