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With age, the compliance of cardiac valves to mechanical stress decreases, making them susceptible to degeneration, which is typically manifested as mitral valve calcification

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"It is important to remember that alcohol isn't a benign substancedrinking too much is associated with a higher risk of most cancers, heart disease, high blood pressure and depression." Frequently Asked Questions How much water should you drink while drinking alcohol

Due to these properties, they represent promising candidates for the development of more stable and efficacious research compounds, particularly when targeting proteinprotein interactions