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In these transgenic mice, optogenetic stimulation of the circuit connecting the posterior basolateral amygdala (BLA) to calbindin-positive neurons in the ventral hippocampal CA1 alleviates anxiety-like behavior, suggesting hypoactivity of the calbindin-positive neurons (Pi et al., 2020)

Pricing is a flat $99/monthup to 70% less than brand-name alternatives like Wegovy ($149$349/month) and Zepbound ($299/month)

Drug-specific effects on oral medication exposure : Some GLP1 agents have labeling cautions about oral drug absorption or recommend backup contraception during initiation/dose escalation (this varies by medication)

Independent testing exposes major differences between brands