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2 Of these adverse effects, gastrointestinal effects are most commonly reported

Potential Interactions and Safety Considerations While direct drug-drug interactions between Wegovy and ibuprofen are not established, several safety considerations merit attention when using these medications concurrently

Given the lack of individual preclinical models of PCOS that recapitulate all the metabolic, endocrine, and gonadal traits of the clinical syndrome, pharmacological testing was conducted in parallel in these two PCOS models, which are among the most reliable to mimic the metabolic and gonadal phenotype of women with PCOS 36,37 , capturing also the heterogeneity of this condition 38