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Patients with favorable GLP1R variants (rs6923761) may achieve excellent results with semaglutide monotherapy, while those with strong GIPR activity (rs1800437) tend to respond better to tirzepatide's dual mechanism
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Some important factors to consider include allergic responses, injection site reactions, electrolyte imbalances, kidney and liver function, skin-lightening concerns, drug interactions, gastrointestinal disturbances, and long-term safety
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