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Studies have reported OCTN2 expression in respiratory epithelial cells and alveolar macrophages, which is especially high in the upper lung region [301], and OCTN2-mediated carnitine uptake plays an important role in maintaining respiratory cilia beating and airway mucociliary clearance function, helping to remove excess mucus and potentially harmful substances from the airway [302]

Inhibition of SLC38A5 enhances the sensitivity of gemcitabine-resistant pancreatic cells to ferroptosis [155]

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doi: 10.1016/j.nut.2014.10.001 5