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Ferroptosis inhibitors, particularly Ferrostatin-1, have been shown to effectively suppress ferroptosis under various pathological conditions (152, 176)

The DLD encoded proteins are also functional components of the 2-oxoglutarate dehydrogenase complex (more commonly known as -ketoglutarate dehydrogenase) of the TCA cycle described below, and of the branched-chain keto acid dehydrogenase complex (BCKD, involved in branched-chain amino acid metabolism)