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This is called a therapeutic cascade

The present review elucidates the molecular mechanisms underlying the lactate-ferroptosis axis, examining how lactate influences ferroptosis through lactylation-independent and -dependent pathways that modulate iron homeostasis, lipid metabolism, redox balance and the immune response

So I think recognizing that youre kind of in a losing position from the start against that environment is realistic, and its a good sort of first step

Fifth, due to limited numbers of study subjects in different individual GLP-1RA and insulin therapies, further assessment of comparative effectiveness and cost-effectiveness of treatments by the more granular level of different individual drugs would be underpowered