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You can take NSAIDs or acetaminophen, wear knee sleeves, and use poles while hiking, but when the pain gets bad enough, you end up with knee replacement surgery

Supplement Facts: Serving Size: 1 capsule Servings Per Container: 90 Amount Per Serving: Vitamin C: 40 mg (50% RI) Niacin: 4 mg NE (25% RI) Vitamin E: 3 mg -TE (25% RI) Pantothenic Acid: 1.50 mg (25% RI) Vitamin B6: 0.35 mg (25% RI) Riboflavin (Vitamin B2): 0.35 mg (25% RI) Thiamine (Vitamin B1): 0.28 mg (25% RI) Vitamin A: 200 g RE (25% RI) Folic Acid: 50 g (25% RI) Biotin: 12.50 g (25% RI) Vitamin D: 1.25 g (25% RI) Vitamin B12: 0.63 g (25% RI) Malabar tamarind fruit extract (Garcinia cambogia) [60% HCA]: 188 mg Fish collagen peptides: 100 mg Green tea extract (Camellia sinensis) [55% EGCG]: 50 mg CLA (conjugated linoleic acid): 50 mg L-Carnitine: 50 mg Hyaluronic acid: 5 mg Coenzyme Q10: 5 mg *RI - Reference Intake Ingredients: COMPLEX FOR HER [malabar tamarind fruit extract (Garcinia cambogia) [60% HCA], fish collagen peptides, L-carnitine tartrate, calcium salt of conjugated linoleic acid [80% CLA], green tea extract (Camellia sinensis) [55% EGCG], sodium hyaluronate, coenzyme Q10 (ubiquinone)], capsule shell [glazing agent (hydroxypropyl methyl cellulose)], MULTIVITAMIN COMPLEX [vitamin C (L-ascorbic acid), maltodextrin, niacin (nicotinamide), vitamin E (DL-alpha-tocopheryl acetate), pantothenic acid (calcium D-pantothenate), vitamin B6 (pyridoxine hydrochloride), riboflavin, thiamine (thiamin mononitrate), vitamin A (retinyl acetate), folic acid (pteroylmonoglutamic acid), biotin (D-biotin), vitamin D (cholecalciferol), vitamin B12 (cyanocobalamin)], anti-caking agent (magnesium salts of fatty acids)

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Those who did not discontinue tirzepatide and were on a high maintenance dose lost a mean 18% of their body weight