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If you develop NAION while on this medication, it will likely result in permanent visual impairment. Legal Action Against Wegovy Patients who experienced gastroparesis, ileus or NAION-related vision loss after taking Wegovy have filed lawsuits against Novo Nordisk

This choice was intended to avoid potential confounding associated with non-user comparisons and other active comparators that have been linked to a possible excess risk or decrease in risk of major adverse cardiovascular outcomes 27,47

So thats why we do know it is a safe drug actually. A BMI of 30 or higher qualifies on its own

Final thoughts Tesofensine represents a powerful weight loss compound with proven 10-12% average weight loss through triple monoamine reuptake inhibition targeting dopamine, norepinephrine, and serotonin