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Main wins include antioxidant defense, liver support, immune balance, and possible skin tone brightening when paired with vitamin C and sun care
Prior authorization requirements are common, requiring documentation of BMI over 30 kg/m or over 27 kg/m with comorbidities, failed attempts at diet and exercise, and sometimes trial of other weight loss medications
For example, aspirin, which can help alleviate pain, can also cause gastric reflux
Reduction is gated on stored fat: the participants in that substudy all started with at least 10% liver fat, and the size of the drop tracked how much was there at baseline
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