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The concomitant improvement in insulin sensitivity and beta-cell function, which were associated with normalization of glucose levels in people with prediabetes, suggests that tirzepatide treatment may delay and potentially halt progression to T2D, by inducing so-called beta-cell rest and ultimately, modifying the natural history of prediabetes/T2D

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As the weight came off, some felt more motivated to exercise, more at ease being seen in public, more able to build routines that had long felt out of reach

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Handbook of Biologically Active Peptides (2nd ed.)

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2023 -

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