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Tissue Healing and Repair BPC 157 is most well-known for its proposed tissue healing properties, including tendons, ligaments, muscles, and bones, by the following mechanisms: Impacting growth factors: It may activate the JAK2 signaling pathway and increase growth hormone receptor activity, particularly in tendon cells, enhancing their ability to respond to growth hormone
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Common polygenic variation contributes to risk of schizophrenia and bipolar disorder
Gene-level modulation: Pickart & Margolina 2018 documented activity across ~4,000 human genes, with fibroblast expression patterns shifting closer to younger cells
