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These effects were reversed when metformin was reintroduced (Napolitano 2014)
13 Both endogenously secreted GLP-1 and GIP are quickly cleared following release due to both renal clearance and rapid metabolism by the enzyme DPP-4
Plus, it has smaller amounts of stearic and linolenic acid
Compounds from commercial sources were purchased with a minimum purity of 90% and were stored as 50 mM stock in dimethylsulfoxide (DMSO) at 80 C
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