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This rapid clearance might suggest the need for larger doses, yet the peptide initiates cellular processes that continue long after the compound itself has been metabolized

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The interaction between endothelial CD93 and MMRN2 regulates fibronectin deposition during glioma angiogenesis, and loss of endosialin, mainly expressed in pericytes, protects against development of fibrosis, suggesting that this protein family participates in regulating the extracellular matrix [105, 109]